Obese hypogonadal men lost an average of 36 pounds during long-term testosterone replacement therapy (TRT), results of a prospective cohort study showed.
The men also shed 3.5 inches from their waistline as they lost fat mass and added lean body mass to their body composition. Overall, 95% of the 255 men lost weight during TRT for as long as 5 years, and 97% had reduction in waist circumference.
So far as investigators know, the men improved their physical status without really trying, as reported here at the ENDO 2012 meeting.