Results of a study were presented at the 2012 European Congress on Obesity in Lyon , France by Dr Bradley Anawalt, M.D. from The Endocrine Society and the University of Washington Medical Center, Seattle that followed 251 obese men aged 38 to 83 with low testosterone levels. Among these men, 214 were followed for two years and 115 were followed for five years.
The men were given 1,000 milligrams of testosterone by injection when the study started, again at six weeks and then every 12 weeks until the end of the trial. The product used was Nebido (possible upcoming name in the US: Aveed)
The men who were followed for five years lost an average of 35 pounds. Their average body-mass index — a measurement that takes height and weight into account — dropped from 34 to 29, moving them from the obese category into the overweight category. In addition, they also saw improvements in their cholesterol and triglyceride levels, along with their blood pressure.
In addition, there was no increase in the risk of prostate cancer, researchers noted.
Prior studies in conditions like HIV have shown testosterone replacement to decrease fat mass and increase lean body mass.
Testosterone replacement also increases energy levels, so men can exercise more frequently.