The dose used in the US study for Aveed was 750 mg, not the usual 1000 mg approved in most countries. Below is the document submitted to the FDA to explain the coughs issue, etc. The pic shows the dosing in the studies. There was a loading phase and then injections became less frequent. Between 21 and 40 days total T would be under 500 ng/ml. The goal is to be above 300 ng/ml, which will not be enough for most men unless you inject every 750 mg once a month.